Description
Active Ingredient: Rifaximin
KEY POINTS
- Fully available in the uterus
- Effervescent vehicle that rapidly releases the antibiotic
- Zero withdrawal time
COMPOSITION
Each 4 g pessary contains: rifaximin 300 mg.
PHARMACEUTICAL FORM
Intrauterine preparation.
TARGET SPECIES
Cattle, sheep, goats, horses
PROPERTIES
Fatroximin Pessaries contain rifaximin, a synthetically produced antibiotic belonging to the ansamycine family. Pharmacokinetic studies have shown that thanks to its special chemical structure, rifaximin remains within the uterus, not passing through the uterine wall and hence determining optimum drug availability in the uterus as well as leaving no residues at all in the animal’s milk or meat.
Fatroximin Pessaries are endowed with high antibacterial activity against Gram-positive (Arcanobacterium pyogenes, Corynebacterium spp., Staphylococcus spp., Streptococcus spp.) and Gram-negative microorganisms (E. coli, Pasteurella spp., Salmonella spp., etc.), aerobic and anaerobic microorganisms.
Disposable rubber gloves are included.
INDICATIONS
Fatroximin Pessaries are indicated for the therapy and prevention of infections of the female genital tract and more specifically: metritis, endometritis, cervicitis, vulvovaginitis, septic infections following delivery, placental retention, dystocia and prophylaxis following manual or instrumental obstetric manoeuvres.
ADMINISTRATION
DOSAGE
Metritis, endometritis, cervicitis: 4 pessaries in one single administration or 2+2 pessaries at a 24 hour interval.
Vulvovaginitis: 1+1 pessary at a 24 hour interval.
Placental retention: 4 pessaries in one single administration.
Manual or instrumental obstetric manoeuvres (dystocia): 2 pessaries in one single administration.
Sows, ewes and goats:
Metritis, endometritis, cervicitis, vulvovaginitis: 2 pessaries in one single administration or 1+1 pessary at a 24 hour interval.
Placental retention: 2 pessaries in a single administration.
Manual or instrumental obstetric manoeuvres (dystocia): 1 pessary in one single administration.
In cases of placental retention if detachment does not occur within 12-24 hours subsequent to treatment, introduce 2 further pessaries into the uterus.
Administer via vaginal-uterine route.
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