REPEN

Description

Active Ingredient: Benzylpenicillin-dihydrostreptomycin

KEY POINTS

Ready-to-use formulation
Broad spectrum with synergic activity
High stability and excellent syringeability

COMPOSITION

1 ml contains: benzylpenicillin procaine 200,000 IU, dihydrostreptomycin sulphate equivalent to dihydrostreptomycin 250 mg.

PHARMACEUTICAL FORM

Injectable suspension.

TARGET SPECIES

Cattle, sheep, goats, horses, dogs, cats

PROPERTIES

Benzylpenicillin is active against Gram-positive bacteria, whereas dihydrostreptomycin is active against Gram-negative germs and thus provides synergic action to benzylpenicillin.
Furthermore, the presence of a long acting penicillin (benzylpenicillin procaine) ensures a sustained therapeutic action.
The 1:1.25 benzylpenicillin-dihydrostreptomycin ratio endows optimum antibacterial activity upon both antibiotics. Benzylpenicillin is active for 24 h, but no long acting dihydrostreptomycin formulations are available.
By increasing dihydrostreptomycin levels, full therapeutic action can be maintained for 24 hours.

INDICATIONS

Bronchitis, pleuritis, pneumonia, broncho-pneumonia, gastroenteritis, enteritis, actinomycosis, shipping fever, leptospirosis, mastitis, foot rot, polyarthritis, infections of the urogenital system.
Bacterial infections secondary to virosis, infected wounds.
Abscesses, pyoderma and septicaemia.

ADMINISTRATION

IM.

DOSAGE

Cattle, horses: 15-30 ml/day.
Calves, foals: 5-10 ml/day.
Sheep, goats: 5-15 ml/day.
Dogs, cats: 2-10 ml/day.
Repen is administered exclusively via deep IM route.
Use large needles for easier injection.