Description
Active Ingredient: Flumequine
KEY POINTS
- Complete and rapid absorption
- Strong bactericidal activity and quick distribution
- Excellent tolerance even in very young animals
COMPOSITION
1 g contains: flumequine 15 mg.
PHARMACEUTICAL FORM
Oral paste.
TARGET SPECIES
Sheep, goats, dogs, rabbits
PROPERTIES
Flumequine is a quinolone chemotherapeutic agent. The fluorine present in the molecule enhances the activity of the drug. It is active against Salmonella spp., E. coli, Pasteurella spp., Proteus spp., Klebsiella spp., Bordetella spp., Enterobacter spp. and Staphylococcus spp.
Flumequine exerts its activity by inhibiting bacterial protein synthesis through blockage of the DNA-polymerase enzyme, thereby determining a bactericidal effect.
Flumequine administered by oral route is readily absorbed and rapidly distributes to the various compartments of the organism. Plasma half-life varies from 5 to 7 h according to species.
Main excretion route is renal, although a small aliquot is excreted by faecal route.
INDICATIONS
For lambs, kids, rabbits and dogs (puppies). Treatment of salmonellosis, colibacillosis, neonatal infections, respiratory syndromes, pasteurellosis and urinary infections.
ADMINISTRATION
DOSAGE
Lambs, kids: 2 g/2 kg bw (loading dose), 1 g/2 kg bw (maintaining dose).
Rabbits: 2-4 g/2 kg bw (loading dose), 1-2 g/2 kg bw (maintaining dose).
Dogs: 2 g/2 kg bw (loading dose), 1 g/2 kg bw (maintaining dose).
Administer by oral route at 12-h intervals.
Each marking on the pump will deliver 1 g of product.
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