UNACEF

Description

Active Ingredient: Cefadroxil

KEY POINTS

Safe molecule with a high therapeutic index
High cure rates with ‘once a day’ therapy
Palatable and divisible tablets
Broad spectrum of action

COMPOSITION

Each tablet contains:

Unacef 200 mg: cefadroxil 200 mg equivalent to cefadroxil monohydrate 210 mg.

Unacef 1000 mg: cefadroxil 1000 mg equivalent to cefadroxil monohydrate 1050 mg.

PHARMACEUTICAL FORM

Oral tablets.

TARGET SPECIES

Dogs and cats.

PROPERTIES

Cefadroxil, as all cephalosporins, exerts its bactericidal activity by interfering on the bacterial cell wall synthesis during the replication phase.

Cefadroxil action leads to a rapid lysis of the microorganism, resulting in bacterial death.

Cefadroxil presents a broad spectrum of action, which includes both Gram-positive (Staphylococcus aureus, Leptospira spp., Clostridium spp,). and Gram-negative bacteria (including E. coli and Pasteurella multocida) responsible of the most soft tissues, respiratory and urogenital tracts infections of dogs and cats.

The prolonged efficacy of cefadroxil is a consequence of the post-antibiotic effect of this molecule, particularly longer than with other cephalosporins of the same generation.

This feature allows cefadroxil to inhibit bacteria growth, even at lower concentrations than the MIC.

INDICATIONS

Skin infections and soft tissues infections (cellulitis, pyoderma, infected wounds and abscesses); urogenital infections (cystitis, nephritis, metritis, vaginitis); respiratory infections (pneumonia, tonsillitis, upper respiratory; airways infections).

ADMINISTRATION

Oral.

DOSAGE

The recommended oral dose of cefadroxil is 20 mg/kg per day.

In the therapy of particularly severe cases, the dose can be doubled. In these cases it is recommended to split the dose in two daily administrations.

The treatment should be continued for at least 48 hours after the disappearance of the fever or other symptoms.