Description
DIRECTIONS:
Boviral 4 ® is recommended for the prevention of respiratory complications in bovines which can be triggered in the presence of a viral group formed by the following micro-organisms: Infectious Bovine Rhinotracheitis Virus (IBR), Bovine Viral Diarrhea Virus (BVD), Parainfluenza Virus 3 (PI-3) and Bovine Respiratory Syncytial Virus (BRSV). Boviral 4 ® is a suspension of attenuated virus of colored IBR strain, DVB genotype 1a, New York genotype 1b and genotype 2, cytopathic and un-cytopathic biotypes, Bovine Respiratory Syncytial Virus (BRSV) and Parainfluenza Virus 3 (PI-3), with aluminum hydroxide gel as excipient. The administration of this vaccine prevents respiratory complications sometimes associated with bacterial agents which can trigger respiratory symptoms, fever, tearing, depression, dyspnea, cough and nasal secretion. In other cases, animals affected by the virus can show vaginitis, balanoposthitis, abortions, enteritis, conjunctivitis, encephalitis and general affections in newborns; which is why the vaccination with Boviral 4 ® is of the utmost importance.
DOSAGE:
For the first immunization on calves, we recommend the application of a 5.0 ml dose before weaning, repeat the process at the age of 4 weeks and administrate the booster shot at the age of 6 months. For adult bovines, one 5.0 ml dose annually. For cows and heifers, we recommend the administration between 30 and 90 days before the insemination.The administration is allowed for pregnant animals.
ADMINISTRATION ROUTE:
Intramuscular only.
WARNINGS:
Just like any other biological product, some anaphylactic reactions can occur. Antidote: administrate epinephrine followed by symptomatic therapy. In cases when the animal is sick, malnourished, with parasites, stressed, immunocompromised, when living in harsh climatic conditions or when the vaccine is not administrated according to the laboratory?s instructions, some animals can develop a protective immune response. Keep in a dry and cool place. Keep away from sunlight. Keep refrigerated between 4°C and 8° C. Avoid heating or freezing. Shake before each application. Use sterile syringes and needles for the administration of this product. Keep out of reach of children. This product is exclusively for veterinary use.
FORMULA:
Every 5.0 ml dose contains:
In equivalent proportions, inactivate virus:
Infectious Bovine Rhinotracheitis Virus (IBR) no less than ………………………………………………………………. 106.5 CCID* 50%/ dose
Parainfluenza Virus 3 (PI-3) no less than ………….106.5 CCID* 50%/ dose
Bovine Viral Diarrhea Virus (BVD) type I & II no less than ……………………………………………………………….106.5 CCID* 50%/ dose
Bovine Respiratory Syncytial Virus (BRSV) no less than ………………………………………………………………..106.5 CCID* 50%/ dose
Vehicle q.s. (Injectable distilled water) …………………………………….5 ml
*CCID (Culture Cells Infective Dose.
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