Active Ingredient: Enrofloxacin


  • Broad spectrum of action
  • Potent bactericidal effect
  • Wide distribution and optimum tissue penetration


1 ml contains: enrofloxacin 100 mg.


Injectable solution.


Cattle, sheep, goats


Valemas 10 is a solution for injection based on enrofloxacin, a synthetic chemotherapeutic agent developed specifically for use in veterinary medicine, belonging to the group of quinolone carboxylic acid derivatives. The mechanism of action of enrofloxacin is exerted through intranuclear inhibition of DNA gyrase. In this way, all the vital functions of the microorganism are blocked with a rapid bactericidal effect.
The antibacterial spectrum of enrofloxacin extends not only to Gram-negative microorganisms (such as E. coli, Salmonella spp., Proteus spp., Pasteurella spp., Bordetella spp., Haemophilus spp. and Pseudomonas spp.) but also includes Gram-positive microorganisms (Streptococcus spp., Staphylococcus spp. and Clostridium spp.) and particularly the mycoplasmas typical of all domestic species (Mycoplasma gallisepticum, M. synoviae, M. bovis, M. hyopneumoniae, M. hyorhinis, M. hyosynoviae, M. meleagridis, M. iowae and Ureaplasmas).
Enrofloxacin has a marked distribution throughout the animal organism and is well absorbed in all species. Peak serum levels are reached within 2 hours of administration and concentrations remain higher than the MICs or MBCs up to 24 hours after each single administration.
Valemas 10 is characterised by a high volume of distribution which guarantees high tissue penetration. The maximum concentrations reached by enrofloxacin in organic fluids (bile, urine, joint fluid, cerebrospinal fluid, aqueous humor and milk) and in the intestinal contents, are from 2 to 3 times higher than serum levels.
This makes Valemas 10 efficacious in therapy of severe systemic infections in various animal species.


Valemas 10 is broad-spectrum antibacterial agent used for therapy of primary bacterial infections or infections secondary to virosis, to all organs and systems. Calf and beef calf: individual or enzootic infections due to Gram-positive and Gram-negative microorganisms, mycoplasmas and mixed microbial flora, to all organs and systems: bronchitis, bronchopneumonia, pneumonia, gastroenteritis, enteritis, nephritis, cystitis, uritis, and omphalitis.
Adult cattle: infections caused by Gram-positive and Gram-negative microorganisms and mycoplasmas to the gastroenteric system, the respiratory system and the urogenital system. Also in the course of acute metritis and metroperitonitis, acute mastitis, and as post-surgical antibiotic protection.
Sheep, goats: pasteurellosis, clostridiosis, colibacillosis in the lamb and goat kids, acute mastitis, gangrenous mastitis (for a quoad vitam outcome of therapy), contagious agalactia.

In particular, in the course of pleuropneumonia due to Haemophilus, enzootic pneumonia due to mycoplasmas also complicated by secondary infection microorganisms, atrophic rhinitis etc. Acute, subacute, chronic or tardive neonatal enteritis due to sensitive microorganisms such as diarrhoea due to E. coli, colibacillosis and salmonellosis in general. MMA complex, acute mastitis, metritis, and puerperal fever.




Valemas 10 is to be administered to cattle, sheep, goats at a dose of: 0.5 ml/20 kg bw every 24 hours (equivalent to 2.5 mg of enrofloxacin/kg bw/day) for 3-5 consecutive days.
Use the slow intravenous or subcutaneous routes in cattle; preferably subcutaneous administration in sheep and goats, intramuscular administration in swine and preferably subcutaneous in the other species, up to a maximum of 10 ml per injection site if the SC or IM routes are used.
In cases of severe respiratory infections and in the course of salmonellosis, the dosage may, if necessary, be increased to 5 mg of enrofloxacin/kg bw every 24 h for 5 consecutive days.


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